Not on the Acer Aspire One but on the MSI Wind Notebook, which isn't all
that different. I have installed Ubuntu (and many other distros!) from my
external USB DVD drive and also from a flash drive. I've found Unetbootin
makes it easy to install most distros onto a flash drive.

Other than that the installation is pretty straightforward. I should mention
that I replaced my original WiFi card with an Atheros one. Enabling WiFi may
be an issue to be resolved on your device.

Sometimes you can't see the bottom of windows which are expecting a 4:3
aspect screen. Using alt when you drag usually makes it possible to lift the
screen enough to see the buttons. Or you may use alt- and the key letter,
usually C(lose) or F(orward).