So you want to have the Excel script run  instead of ASP/PHP as a web  server?
No. Not unless you write your own web server.

I believe that there is ASP code that will convert worksheets to HTML and allow
some of interaction with the individual "cells". Do a Google search and you'll
probably find what you want. (I've never bothered with them, so can't point you
anywhere - all my ASP work is database-based.)