The Range goes to the last cell in the first column ,A65536, and then goes to the top, A1. The Offset part of your code then takes you to the second row first column.
Range("A1”).Offset(1, 0).Select would do the same thing.
Selection.Offset(1, 0) would take you to the cell below the current cell
And
Selection.Offset(0,1) would take you to the cell to the right of the current cell.